Herbosomes: A Current Concept of Herbal Drug Technology An Overview

Shukla Ajay *, Pandey Vikas,, Shukla Rajesh, Bhatnagar Punit, Jain Suchit 

Guru ram das khalsa technology & science, Jabalpur 

ABSTRACT

Herbosome is a current concept in herbal drug technology that removes the limitations of the traditional drug delivery systems. Herbal medicines have been widely used all over the world since ancient times and by physicians and patients for their better therapeutic value as they have no or less side effects as compared with modern medicines. The Herbosome structures contain the active ingredients of the herb bounded to phospholipids. The molecular structure of phospholipid includes a water-soluble head and two fat-soluble tails. Because of this dual solubility, the phospholipid acts as an effective emulsifier. By combining the emulsifying action of the phospholipids with the standardized botanical extracts, the herbosome form provides dramatically enhanced bioavailability for lipid soluble drugs explained by faster and improved absorption in the intestinal tract. Herbosome technology has been effectively used to enhance the bioavailability of many popular herbal extracts and phytoconstituents including Ginkgo biloba, milk thistle, grape seed, green tea, hawthorn, ginseng etc. and can be developed for various therapeutic uses or dietary supplements. This method can enhance the rate and the extent of drug absorption across the lipoid bio-membrane, which has been found promising for effective and appropriate systematic delivery of drug.

Keywords: Herbosomes, Phosphatidylcholine, Polyphenol, Liposomes, Herbosome complex.