BILAYER TABLETS

Navidita Sharma*, Sonia Pahuja, Nancy Sharma, Naveen Sharma

Swami Vivekanand College of Pharmacy, Banur, Punjab, India

ABSTRACT

Among various dosage forms used for oral drug delivery, bilayer tablet technology is one of the most successful and popular technology as it provides several advantages over conventional dosage forms. It is suitable for release of two drugs which may be incompatible with each other as this technology allows us to separate such drugs. One of the two layers may be immediate release as initial dose and second layer as sustained release is maintenance dose. In this way, gradual drug level is achieved in blood. It also overcomes the shortcomings of single layered tablets. In this article, various techniques and approaches for bilayer tablets have also been discussed such as floating bilayer tablets, geomatrix tablets, swelling bilayer tablets and polymeric bio adhesive bilayer tablets.

Keywords:

Bilayer tablets, controlled release, immediate release, floating bilayer tablets, polymeric bio adhesive bilayer tablets.