Comprehensive review on method development of galantamine

Trinita Debe Padmaja, S Ramachandran, M Vijey Aanandhi

Department of Pharmaceutical Analysis, School of Pharmaceutical Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Pallavaram, Chennai, Tamil Nadu. India.

Refer this article

Trinita Debe Padmaja, S Ramachandran, M Vijey Aanandhi, 2022. comprehensive review on method development of galantamine. Journal of medical pharmaceutical and allied science V 11 - I 5, Pages - 5264 – 5267. Doi: 10.55522/jmpas.V11I5.3919.

ABSTRACT

Galantamine is generally common in the treatment of Alzheimer’s in old people. Galantamine is also used in combination treatments for Alzheimer. Different analytical techniques such as Liquid Chromatography-Mass Spectrometry, Reverse Phase-High Performance Liquid Chromatography,High Performance Liquid Chromatography, Ultra Performance Liquid Chromatography, and Ultraviolet Visible spectrometric method areused in the determination and validation of galantamine and its interactions. Different articles were reviewed and the results were found to be accurate and prudent in determining galantamine in human plasma and also other body fluids. Pharmacokinetic and bioequivalence investigations performed in different articles were summarized. All the methods stated in this article proves precise values and were found to be successful in determining and validating the drug galantamine and its interactions.Every method reviewed in this article are different from each other. This article summarizes few of the developed and validated analytical techniques available for the determination/ estimation/quantification and validation of Galantamine

Keywords:

Galantamine, Alzheimer disease, LC-MS, UV spectrometry, RP-HPLC

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