Current advances in dry eye disease diagnosis and treatment

Ashish Kumar Sahoo, Amit Patil, M P Venkatesh, Praveen Halagali

Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research (JSSAHER), Mysuru, Karnataka, India.
Faculty of Pharmaceutical Sciences, USCI University, Kuala Lumpur, Malaysia.

Refer this article

M P Venkatesh, Ashish Kumar Sahoo, Amit B Patil, Praveen Halagali, 2023. Current advances in dry eye disease diagnosis and treatment. Journal of medical pharmaceutical and allied sciences, V 12 - I 2, Pages - 5724 – 5724. Doi: 10.55522/jmpas.V12I2.4952.

ABSTRACT

Dry eye disease (DED) is a disorder of the ocular surface caused due to hyperosmolarity and insufficient production of tears to moisturize the eye, which leads to less lubrication and ocular surface inflammation and results in visual disturbance and discomfort to the eye. Long-time use of computers, laptops, and mobiles causes less blinking, making the eye's mucin layer thinner, leading to tear-film instability and DED. Tens of millions of people are getting affected by DED worldwide. It is also known as Sjogren's syndrome, which impacts the lacrimal gland of the eyes, decreases tear secretion, and causes the development of aqueous tear film in the eyes and meibomian gland dysfunction. Here we have discussed the various diagnosis methods used for identifying DED and also the emerging technologies for the diagnosis of DED. The treatment options are discussed as per the disease's severity, including novel therapies like the autologous serum, topical corticosteroids, and anti-inflammatory agents.

Keywords:

Dry eye disease, Tear film, Inflammation, Sjogren's syndrome.

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