The effect of robust coffee towards the malondialdehyde level in healthy adults

Anita Lidesna Shinta Amat, Herman Pieter Louis Wungouw, Prisca Pakan

Faculty of Medicine and Veterinary Medicine, Universitas Nusa Cendana, Indonesia.

Refer this article

Anita Lidesna Shinta Amat, Herman Pieter Louis Wungouw, Prisca Pakan, 2023. The effect of robust coffee towards the malondialdehyde level in healthy adults. Journal of medical pharmaceutical and allied sciences, V 12 - I 4, Pages - 5983 – 5986. Doi: https://doi.org/10.55522/jmpas.V12I4.5562.

ABSTRACT

Coffee contains more than a thousand molecules, including phenolic compounds, vitamins, minerals and alkaloids. Caffeine, cafestol, kahweol and chlorogenic acid are related to lipid metabolism and can affect serum lipid profiles. Clinical studies have reported the effects of caffeine on cardiac arrhythmias, liver function, serum cholesterol and blood pressure. Malondialdehyde (MDA) in the human body is a by-product of free radicals (oxidative stress), which can indicate whether oxidative stress is detrimental. This study aims to analyse the effect of strong coffee on MDA levels in healthy adults. This study used a quasi-experimental design with a nonequivalent control group. This design was divided into two groups: the treatment group and the control group. The treatment group was given the treatment of drinking coffee and not eating foods that can raise cholesterol. In the control group, they did not drink coffee or eat foods that could cause increased malondialdehyde levels. The results showed that coffee increased MDA levels in 91% of the samples. Thus, strong coffee can increase malondialdehyde (MDA) levels in healthy adults.

Keywords:

Robust, Coffee, Malondialdehyde, MDA.

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