Detection of pulmonary tuberculosis and rifampicin resistant tuberculosis from sputum samples in a tertiary care hospital, Delhi & NCR, India

Nikita, Monika Mogha1 Nikhil Payal*, Manisha Khandait, Mohit Bhardwaj, DPS Sudan

Department of Microbiology, Faculty of Medicine & Health Sciences, SGT University & Hospital, Haryana, India

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Nikita, Monika Mogha, Nikhil Payal, Manisha Khandait, Mohit Bhardwaj, DPS Sudan, 2024. Detection of pulmonary tuberculosis and rifampicin resistant tuberculosis from sputum samples in a tertiary care hospital, Delhi & NCR, India. Journal of medical pharmaceutical and allied sciences, V 13 - I 3, Pages - 6598 – 6602. Doi: https://doi.org/10.55522/jmpas.V13I3.6447.

ABSTRACT

This study examines pulmonary TB diagnosis and Rifampicin resistance in sputum samples from a Delhi tertiary hospital. Findings indicate a 3.08% TB prevalence, significant gender differences, and morning specimens' diagnostic superiority. Mycobacterium tuberculosis (TB) ranks second only to the Human Immunodeficiency Virus (HIV) in terms of infectious disease-related deaths, and it also plays a significant role in the development of antibiotic resistance worldwide [1]. The Mycobacterium tuberculosis complex is responsible for transmitting it, making it one of the oldest diseases known to affect humans and a major cause of death on a global scale [2]. Mycobacterium tuberculosis is a thin, aerobic bacterium that measures 0.5 x 3 m, is rod-shaped, and is non-spore-forming in nature. Acid-fast microorganisms are known as mycobacteria.

Keywords:

Latent TB, Mycobacterium, Rifampicin, Multi-drug Resistant, Pulmonary Tuberculosis

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