Survival outcomes of billroth-I reconstruction following distal gastrectomy for gastric cancer patients in Vietnam: A 5-year follow-up

Dang Tien Ngoc, Trinh Hong Son*, Nguyen Dang Vung, Nguyen Hoang Thanh, Nguyen Dac Ca, Le Hong Trung, Do Trong Can, Le Van Tinh

Viet Duc University Hospital, Hanoi, Vietnam

Refer this article

Dang Tien Ngoc, Trinh Hong Son, Nguyen Dang Vung, Le Hong Trung, Do Trong Can, Le Van Tinh, Nguyen Dac Ca, Nguyen Hoang Thanh, 2024. Survival outcomes of billroth-I reconstruction following distal gastrectomy for gastric cancer patients in Vietnam: A 5-year follow-up. Journal of medical pharmaceutical and allied sciences, V 13 - I 3, Pages- 6617– 6622. Doi: https://doi.org/10.55522/jmpas.V13I3.6412.

ABSTRACT

This study aims to describe the long-term survivorship of Billroth I (or Pean's) reconstruction technique in patients with distal gastric cancer. A single-arm longitudinal observational study was conducted at Viet Duc University Hospital, Hanoi, Vietnam, from 2018 to 2021. A total of 103 patients who were diagnosed with primary carcinoma in the lower third of the stomach and underwent lower pole gastrectomy with Péan anastomosis were recruited. The Kaplan–Meier analysis was used to estimate the survival outcome. A multivariate Cox proportional hazard regression model was used to measure the factors associated with survivorship. Results showed that 8.7% died during the study period. The Restricted Mean Survival Time (RMST) was 61.9 (95%CI=59.4-64.4) months. RMST was significantly different across the stages of cancer, T and N. Specifically, patients with advanced stage (III) had a substantially lower RMST (49.2 months) compared to those with early-stage (I&II). Patients with T4 or N3 also had the lowest RMST compared to those with other characteristics (p<0.05). Female patients had a lower risk of dying than their male counterparts (HR=0.092, 95%CI=0.013-0.661). Patients with a higher level of Node (N) had a significantly higher risk of dying than those with a lower level (HR=5.103; 95%CI=1.716-15.178). Having comorbidities was associated with a lower risk of dying (HR=0.066; 95%CI=0.008-0.531) than not having comorbidity. To conclude, the findings indicate favourable long-term results for patients with distal gastric cancer undergoing the Billroth I (or Pean's) reconstruction technique. The practice above may be the established protocol for managing these particular patients.

Keywords:

Survival outcome, Billroth-I Reconstruction, Pean anastomosis, Distal gastrectomy, Gastric cancer.

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