A retrospective study of anti-microbial susceptibility pattern among bacterial strain isolated from cases of urinary tract infection

Sristi Singh, Pradyot Prakash, D S Seetharam*, Sharangouda J Patil

Department of Botany, Osmania University, Hyderabad, Telangana State, India

Refer this article

Sristi Singh, Pradyot Prakash, D S Seetharam, Sharangouda J Patil, 2025. A retrospective study of antimicrobial susceptibility pattern among bacterial strain isolated from cases of urinary tract infection. Journal of medical pharmaceutical and allied sciences, V 14 - I 3, Pages - 70 – 79.
Doi: https://doi.org/10.55522/jmpas.V14I3.6792.

ABSTRACT

Urinary Tract Infections (UTI) are common among the individuals and most prevalent bacterial infections seen in clinical practice. It has been observed that nosocomial infection was most common in many hospitals. The study findings shows the causative agents for UTI’s were antibiotics and they exhibit poor patterns of antimicrobial sensitivity. The Institute of Medical Science, Banaras Hindu University (IMS-BHU), which serves a large number of partially treated or maltreated patients, may have various etiological agents and sensitivity patterns. To investigate the range of bacterial infections causing UTI among patients, as well as their antibiotic sensitivity pattern. This retrospective investigation was carried out from January 2020 to December 2020 at the Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Clean catch midstream urine samples were collected from all suspected UTI patients. The urine samples were cultured and tested for antibiotic susceptibility in accordance with normal standards. A total of 8,059 urine samples were tested for urine culture and sensitivity. A total of 1,109 samples were found to be positive for bacterial Infections. To facilitate analysis, positive isolates (n = 1,109) were further classified as Enterobacteriales (n = 791), NLF oxidase-positive (P. aeruginosa; n = 87), NF (Acinetobacter; n = 6), Enterococcus (n = 175), and others. Patients with UTI who present to a tertiary hospital are found to have several bacterial infections. As the antimicrobials recommended for these isolates differ as per the CLSI guidelines, it is essential to determine antimicrobial sensitivity of these isolates is very crucial.

Keywords:

Antimicrobial susceptibility pattern, Bacterial isolates, Gram - Gram-negative bacteria, Urinary tract infection, Antibiotic susceptibility.

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