Evaluation of Antiinflammatory Activity of Synthesized Novel Acridone Derivative

ABSTRACT

Acridones are well known and essential hetero or polycyclic compounds with a tricyclic ring having nitrogen at 10th position and keto group at 9th position. Numerous acridone derivatives have been found to serve important biological activities, which provide the novel research approches in medicinal chemistry areas. They have several prominent effects, such as anti-malarial, anti-microbial, anti-inflammatory, anti-fungal, anti-leishmanial, anti-viral and anticancer activities. The planar structure of these acridones facilitates to act on nucleotides by intercalating DNA and RNA strands, there by prove as potent anticancer agents. Here cover the biological research activity (Anti-inflammatory) provides an insight view to Acridone synthesis of N-(substituted phenyl) anthranilic acid and its biological activities.

Keywords: Acridone, anthranilic acid, anti-inflammatory activity