EXPERIMENTAL INTERVENTION TO PREVENT FLUORIDE EXPOSURE

Purnendu Kumar Sharma, Chaitanya P, Aditya G Reddy, GVishwanathan, A Jaswanth, Vivek Singh Malik

Sri Krupa Institute of Pharmaceutical Sciences, SIDDIPET, Andhra Pradesh, India

Refer this article

Purnendu Kumar Sharma, Chaitanya P, Aditya G Reddy, GVishwanathan, A Jaswanth, Vivek Singh Malik, 2013. Experimental intervention to prevent fluoride exposure. Journal of medical pharmaceutical and allied sciences, V 2 - I 5, Pages -94 – 96. Doi: https://doi.org/10.55522/jmpas.V2I5.0025.

ABSTRACT

This study is attempted to develop a preventive measure against fluoride exposure in the endemic areas of India and other countries. This Experimental approach involves prevention of fluorosis with Calcium lactate and Ascorbic acid. The water samples were collected from endemic areas of Nalgonda district and its fluoride levels were estimated; and considered as fluoride control. The animal study on prevention of fluorosis was performed on 24 Wister albino rats which were divided into four groups. It was found that calcium lactate and ascorbic acid binds to fluoride ions in the GIT and forms an insoluble complex which significantly (P<0>

Keywords:

Fluorosis, skeletal fluorosis, Pre-clinical, Water.

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