Sivazeena.T.S, K.G.Revikumar, M.A.Kuriachan, Veena.R

DOI:

VOLUME-5, ISSUE-12

PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF THE SEEDS OF AGLAIA ROXBURGHIANA

Sivazeena.T.S, K.G.Revikumar, M.A.Kuriachan, Veena.R

1. Department of Pharmacy, Meenakshi Academy of Higher Education and Research, West K.K.Nagar, Chennai, Tamilnadu, India.

2. Director & Principal,KMSCL Institute for Drug Studies, Red Cross Road, Thiruvananthapuram – 35,Kerala,India.

3. Principal, Mar Dioscorus College of Pharmacy, Alathara, Sreekaryam, Thiruananthapuram, Kerala, India.

4. Sr Lecturer, University College of Pharmacy, M. G. University, Cheruvandur Campus, Ettumannur. P.O, Kottayam, Kerala, India

ABSTRACT

Objective Aglaia roxburghiana, family Meliaceae, is a widely used medicinal plant for the treatment of numerous diseases. Although bark, roots, stem, leaves and seeds claim medicinal importance, only a few of the properties have been validated. To provide a scientific base to its popular use, a phytochemical analysis of the aqueous and organic extracts of the seeds were done followed by evaluation of antibacterial activity. Method The presence or absence of phytochemicals was detected qualitatively by chemical methods. The antibacterial activity of the seed extract was determined by Agar well diffusion method. Result The aqueous and organic extracts of the seeds revealed the presence of many secondary metabolites. Assessment of antibacterial activity showed positive results. Conclusion: The results indicate that the ethanolic seed extract of Aglaia roxburghiana could be a safe and potential candidate for the development of new strategies to treat bacterial infections.

Keywords: Aglaia roxburghiana, phytochemical evaluation, antibacterial activity, Agar well diffusion method

Full Text Article