STUDY OF THE ADVERSE DRUG REACTIONS IN CANCER PATIENTS IN GOVERNMENT HEAD QUARTERS, KRISHNAGIRI

Dr. Joshin Sara Cherian*, Dr. Joel Thomas, Dr. Vijay M C

Padmavathi College of Pharmacy and Research Institute, Krishnagiri, Periyanahalli, Dharampuri, Tamilnadu, India.

ABSTRACT

Pharmacovigilance plays a vital role in ensuring that cancer patients receive appropriate medical products that are safe and effective, but very few studies has been done in past on Clinical oncology setup . Adverse drug reactions (ADRs) are an important clinical issue and a serious public health risk. ADRs leading to hospitalization or occurring during hospital stay contribute significantly to cancer patient morbidity and mortality as well as representing an additional cost for healthcare systems. Chemotherapy, a multimodal approach to oncological treatment, involves highly complex regimens and hence accounts to high susceptibility toward ADRs. The study was conducted in the North eastern part of Tamilnadu with less literacy rate and high rate of incidence in sexually transmitted disease. Understanding the underlying mechanisms by the Clinical Pharmacist is critical for clinical diagnosis and management of different ADRs at its early stage in oncology departments. The present study was conducted to assess the chemotherapy induced adverse drug reactions in patients of cancer of oncology department patients in Government Head Quarters Hospital, Krishnagiri and Tamilnadu for a period of 6 months from December 2015 to May 2016.

Keywords:

Pharmacovigilance, chemotherapy, adverse drug reactions, oncology