EVALUATION OF IN VITRO ANTI ARTHRITIS ACTIVITY OF GARCINIA CAMBOGIA FRUIT AGAINST THE DENATURATION OF ALBUMIN

J.priyadharisini*

Jagdish Prasad Jhabarmal Tribewala University, Jhunujunu, Rajasthan, India

ABSTRACT

To evaluate the anti-arthritis activity in vitro in chloroform extract of Garcinia cambogia fruit against albumin denaturation. In controlled experimental condition egg albumin was incubated in with different concentration of chloroform extract and subjected to determination of absorbance to evaluate the percentage of protein inhibition for Anti-arthritis activity using Diclofenac sodium as the standard drug. Dose dependent increase in the percentage inhibition was found as a result. Inhibition of albumin denaturation was observed for all the concentration of the chloroform extract of Garcinia Cambogia fruit. From the current study it can be concluded that Garcinia cambogia fruit possessed marked In vitro Anti-arthritis activity effect against denaturation of albumin. The effect was due to xanthone present as one of the phyto chemical components in of Garcinia cambogia fruit.

Keywords:

Garcinia cambogia, Anti-arthritis, Albumin denaturation, Absorbance