DESIGN AND CHARACTERIZATION OF HYDROGEL FORMULATIONS CONTAINING ALOE VERA AND NEEM SEED OIL

Dr. CH Ajay Babu, Dr. M Prasada Rao, N Anitha*, S Bhargavi Latha, CH Lakshmi Anusha, K Parishudda, S Pragathi

MAM College of pharmacy, Guntur, Andhara Pradesh, India

ABSTRACT

Main aim and objective of the present study is to reduce the resistance caused by the oral The antibiotics which are used in the treatment of the dermatological infections by formulating the transdermal hydrogels by using Aloe Vera extract and Neem Seed oil as active ingredients, Carbopol 934 is used as polymer, Triethanolamine is used as pH and consistency modifier, Methyl Paraben and Propyl Paraben is used as Preservatives and Propylene Glycol is used as Solubility enhancer and as well as Moisturizer. The formulated hydrogel was evaluated for the Viscosity, Spreadability, Drug content and Strength of the Hydrogel and as well as it is evaluated for the Antibacterial activity by using Bacillus Subtilis.

Keywords:

Transdermal, Hydrogel, Aloe Vera Extract, Neem Seed Oil, Carbopol, Anti-Bacterial Activity