DRUG REPOSITIONING IN THE TREATMENT OF COVID-19

Ravella Sai Yamini, Ravella Sai Bhargavi, Kotha Bhuvaneswari

Vignan Pharmacy College, vadlamudi, Andhara Pradesh, India

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2, also known as2019-NCOV), occurred as a worldwide with high death and disease rates. However, at present there are no specific drugs for the cure of 2019-ncov/SARS-cov-2. Clinicians are left with general supportive care and often available treatment options. Drug repositioning commonly called as drug repurposing and it is otherwise called as drug re-profiling. It is the practice of renewing a drug for use in another disease. An antiviral medication used to treat and prevent the viral diseases (including HIV), and antimalarial drugs are found to show activity against the SARS-cov-2. We aimed to review the evidence supporting the repurposed drugs in the cure of coronaviruses and to discuss their potential in SARS-CoV-2.

Keywords:

Novel Coronavirus, COVID-19, repurposed drugs, antiviral agents, antiviral drugs, antimalarial drugs, SARS-CoV-2