STEPS OF ATHEROSCLEROSIS AND ITS COMPLICATION

Monaji Sanjana Reddy

Samskruti College of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana, India

ABSTRACT

Atherosclerosis is hardening, losing of stiffness of arteries because of athermanous plaque this formation can be seen in the artery wall. Atherosclerosis is silent without any symptoms for years as it takes time to cause narrowing or closing of the artery due to clots and symptoms that occur only after severe narrowing and closing that ceases blood to different body organs that instead lead to many other complications. Plaque is formed of different types of fatty deposits which also include cholesterol, cellular waste products, calcium, and fibrin. Plaque can be seen in the heart, legs, brain, arms, and kidneys. This can give rise to various conditions like coronary heart disease, angina pectoris, carotid artery disease, chronic kidney disease. The likelihood is determined by a combination of acquired and inherited risk factors. There is an increased prevalence of mortality in the United States, Africa, India, and Southeast Asia. The countries of the former Soviet Union hold a dubious distinction of having the highest ischemic heart disease mortality rate. The article gives a detailed description on pathogenesis of athermanous and plaque along with its complications.

Keywords:

Atherosclerosis, complications, formation, HDL, LDL