Diabetic, Cucumispubescens, herbal medicine, glucose

Daswani Bharti R*, Deepika N Mishra, Sagar D Phate

B.J. Government Medical College and Sassoon General Hospital, Pune, Maharashtra, India

ABSTRACT

Stroke is abrupt onset of neurologic deficit, referable to a focal vascular cause. The study was undertaken to analyse treatment strategies adopted for patients with ischemic/haemorrhagic stroke, and associated short-term and long-term outcomes of management protocols. Single-centre, observational study, conducted in 200 stroke patients admitted in medicine department at tertiary care hospital with diagnosis of haemorrhagic/ischemic stroke. Data was collected over 18 months. Patient related information was documented into Case Report Form and analysed for a) Ddescriptive statistics regarding drugs used in patients b) Descriptive analysis of outcome in patients in form of death/survival as also improvement in the stroke specific scores i.e., NIH, Modified Rankin, Barthel c) Odds ratio for studying association between use of various drugs and outcome. Among ischemic stroke patients, most commonly prescribed drug was hypolipidemic agent atorvastatin and anti-platelet drug aspirin, followed by anti-hypertensive amlodipine and anti-coagulant enoxaparin sodium. Among hemorrhagic stroke patients, most commonly prescribed drug was atorvastatin, followed by amlodipine. 94% of ischemic stroke patients survived, 6% died while 88% of hemorrhagic stroke patients survived and 12% died. On the basis of stroke-specific scores, prognostic outcome among ischemic stroke patients showed improvement with use of atorvastatin, aspirin and clopidogrel whereas the hemorrhagic stroke patients showed improvement with use of atorvastatin and amlodipine primarily. In Ischemic stroke patient’s hypolipidemic and anti-platelets were apparently associated with better prognostic outcomes. In Hemorrhagic stroke patient’s better prognostic outcomes were seen in patients receiving hypolipidemic and anti-hypertensive primarily.

Keywords:

Stroke patients, ischemic stroke, hemorrhagic stroke, outcome