Possible etiological factors related with fatty liver diseases other than alcohol

Sanjeev Kumar Gupta, Sunil Kumar, Ramtej J Verma

Bio-Medical Technology and Human Genetics, Gujarat University, Ahmedabad, Gujarat, India

ABSTRACT

Non-alcoholic Fatty liver disease (NAFLD) is an ailment that is associated with various causative factors other than alcohol consumption. It affects a substantial number of individuals both young and old irrespective of sex around the globe and its incidence is increasing/rises globally. The data was collected by searching various websites, consulting reports and analysed the data with respect to possible causative factors related to NAFLD in humans. The data available indicated that several factors such as drug addiction/abuse, unhealthy dietary practices, lifestyle habits, diabetic, metabolic disorders, obesity, sedentary lifestyles etc. might be related to non-alcoholic fatty liver disorders in human or exaggerate the NAFLD. Thus, there is a necessity to prevent exposure to such chemicals and/or factors to reduce or prevent this disease and there is also a necessity for an awareness program about the causative factors of NAFLD among the community which could be useful in prevention/control of the ailment. Further, some sort of regular physical exercise, activity and excess weight loss might be useful to check/ control the occurrence/ progression of NAFLD. NAFLD can be prevented/ reduced/ stopped by adaptation of healthy lifestyles in day-to-day life, regular exercise to reduce the weight, and adoption of these in life may be useful in management/ control of disease.

Keywords:

Fatty liver disease; Non-alcoholic liver disease; Non-alcoholic steatohepatitis; Cirrhosis; Metabolic disorders