Glycemic control outcomes and associated factors among inpatients with type 2 Diabetes mellitus and impaired renal function at Can Tho Central General Hospital in 2024

Van-Dung Thach, Thi-Ngoc-Giau Truong*

Tay Do University, 68 Tran Chien Street, Can Tho, Vietnam

Refer this article

Van-Dung Thach, Thi-Ngoc-Giau Truong, 2026. Glycemic control outcomes and associated factors among inpatients with type 2 Diabetes mellitus and impaired renal function at Can Tho Central General Hospital in 2024. Journal of medical pharmaceutical and allied sciences, V 15, I 3, Pages 08 – 16. Doi: https://doi.org/10.55522/jmpas.V15I3.7059.

ABSTRACT

Glycemic control in patients with type 2 diabetes mellitus and impaired renal function is clinically challenging because renal dysfunction may alter glucose metabolism, increase glycemic variability, and raise the risk of hypoglycemia. In this high-risk population, assessing glycemic control outcomes and related factors is essential for improving individualized treatment strategies. This study aimed to determine the rates of glycemic control and identify factors associated with glycemic control outcomes among inpatients with type 2 diabetes mellitus and impaired renal function at Can Tho Central General Hospital in 2024. A retrospective cross-sectional study was conducted using medical records of 310 inpatients with type 2 diabetes mellitus and impaired renal function treated at the Nephrology and Endocrinology Departments of Can Tho Central General Hospital from January to August 2024. Glycemic control was evaluated using fasting blood glucose, HbA1c, and overall glycemic control status. Fasting blood glucose was considered controlled when it ranged from 4.4 to 7.2 mmol/L, while HbA1c was considered controlled when it was ≤7.0%. Overall glycemic control was defined as achieving both fasting blood glucose and HbA1c targets. Associations between glycemic control outcomes and patient characteristics, renal disease status, and treatment-related factors were analyzed using odds ratios, 95% confidence intervals, and p-values. Among 310 patients, 195 patients achieved the fasting blood glucose target, accounting for 62.9%, while 174 patients achieved the HbA1c target, accounting for 56.1%. Overall glycemic control was achieved in 45.8% of patients, whereas 54.2% did not achieve overall control. No statistically significant association was found between fasting blood glucose control and sex, age group, number of comorbidities, admission glucose control status, type of kidney disease, chronic kidney disease stage, or insulin type. Similarly, HbA1c control was not significantly associated with sex, age group, number of comorbidities, admission HbA1c control status, type of kidney disease, chronic kidney disease stage, or insulin type. However, age group was significantly associated with overall glycemic control. Compared with patients younger than 40 years, patients aged 40-<60>

Keywords:

Type 2 diabetes mellitus, Impaired renal function, Glycemic control, Fasting blood glucose, HbA1c, Associated factors.

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