Formulation of nano spray preparation from Purslane Leaf Extract (Portulaca oleracea l.) as sunscreen

Diva Adela Sabrien, Ni’matun Nada Azzahra, Puspa Cinta Ratri Paramitha, Flora Katerrina Desta, Elmiawati Latifah

Faculty of Health Sciences, Department of Pharmacy, Universitas Muhammadiyah Magelang, Magelang, Indonesia.

Refer this article

Diva Adela Sabrien, Ni’matun Nada Azzahra, Puspa Cinta Ratri Paramitha, Flora Katerrina Desta, Elmiawati Latifah, 2024. Formulation of nano spray preparation from purslane leaf extract (portulaca oleracea l.) as sunscreen. Journal of medical pharmaceutical and allied sciences, V 13 - I 1, Pages- 6303 – 6308. Doi: https://doi.org/10.55522/jmpas.V13I1.5890.

ABSTRACT

Purslane plant (Portulaca oleracea L.) is a type of wild plant that grows abundantly, but its benefits are rarely known. Purslane contains saponins, which have high antioxidant and biological activity. Skin that is sensitive to sun exposure is the issue this nanospray is targeting. The aim of this research is to determine the optimal formulation of herbal nanospray products with Purslane sunscreen to treat skin problems caused by sun exposure. The research method used was an experimental method with research stages starting from plant determination, extract making, nanospray formulation determination, preparation evaluation, in vivo UV protection activity test, and in vitro SPF test. Quantitative descriptive analysis was carried out using Microsoft Excel and SPSS Version 24. There were significant differences in erythema (lesions on the skin) between the 4 treatment groups, with significant differences in the negative control and positive control groups, as well as the group given dose treatment (the amount of extract in the nanoparticles) of 0.8 g and 0.4 g of purslane extract with the negative control. So, it can be concluded that doses of 0.8 g (SPF value: 9.9) and 0.4 g (SPF value: 8.43) of purslane extract have the potential to be sunscreens with maximum category and extra protective power. Purslane extract nanospray sunscreen has the advantage of being made from herbal ingredients, which have less potential for irritation than chemical sunscreen products.

Keywords:

Nanospray, sunscreen, Purslane leaf extract, particle size, SPF value

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