A modified claisen- schmidt protocol for synthesis of 1,3-diaryl-2- propen-1-one (chalcone)

Akash Chandrakant Nandanikar*

Department of Pharmaceutics, Appasaheb Birnale College of Pharmacy, Sangli. Maharashtra, India

Refer this article

Akash Chandrakant Nandanikar, 2016. A modified claisen- schmidt protocol for synthesis of 1,3-diaryl-2- propen-1-one (chalcone). Journal of medical pharmaceutical and allied sciences, V 5 - I 3, Pages -277 – 280. Doi: https://doi.org/10.55522/jmpas.V5I3.0091.

ABSTRACT

We here reports a modified improved method for synthesis of 1,3-diaryl-2-propen-1-one, rely on base catalyze condensation of arylmethyl ketone with aromatic aldehyde. This method however to an extent analogues to classical methodology thou minute changes in reactant charging sequence, prominent control over their dropping rate, and strict temperature regulation enhance its synthetic utility. disintegration.

Keywords:

chewable tablet, gum core, antioxidant, compressibility etc.

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