Pentoxifylline: applications in dentistry

Pratik C Parkarwar, Afroz Anjum

Department of OMR PDU Dental College, Solapur, Maharashtra, India

Refer this article

Pratik C Parkarwar, Afroz Anjum, 2017. Pentoxifylline: applications in dentistry. Journal of medical pharmaceutical and allied sciences, V 6 - I 2, Pages -479 – 481. Doi: https://doi.org/10.55522/jmpas.V6I2.0128.

ABSTRACT

Pentoxifylline is a methylxanthine imitative with a range of anti-inflammatory effects presently pentoxifylline is permitted by the Food and Drug Administration for the management of intermittent claudication, but studies have revealed that it has a diversity of physiological effects at the cellular level which may be significant in treating a different group of diseases. Clinical applications of pentoxifylline in dentistry have been reviewed Effects of PTX on different cellules and molecules Anti-TNF-α effects, tumor Necrosis Factor-α is a cytokine with a wide spectrum of activity which is predominantly produced by mononuclear cells. Increasing evidence has implicated TNF-α as a pivotal molecule involved in the pathogenesis of a wide variety of acute and chronic inflammatory disease states including many skin diseases such as psoriasis, graft-versus-host-disease (GVHD), contact dermatitis, leprosy reactions, OSMF, AIDS.

Keywords:

Pentoxifylline, TNF, GVHD, AIDS, OSMF.

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