GC-MS analysis and antimicrobial activity of fixed oil from Saudi Nigella sativa (Ranunculaceae)

Abdel Karim M*, Sufian A, Inas O

Department of Chemistry, Faculty of Science, Sudan University of Science and Technology, Sudan

Refer this article

Abdel Karim M, Sufian A, Inas O, 2017. GC-MS analysis and antimicrobial activity of fixed oil from Saudi Nigella sativa (Ranunculaceae). Journal of medical pharmaceutical and allied sciences, V 6 - I 4, Pages -527 – 529. Doi: https://doi.org/10.55522/jmpas.V6I4.0141.

ABSTRACT

Constituents of Negella sativa seed oil were identified by GC-MS analysis. Major constituents are: methyl 12-hydroxy-9-octadecenoate (17.37%), 9,12,15-octadecatrienoic acid (14.98%), 9-octadecenoic acid methyl ester (12.84%), β-sitosterol (11.95%),9,12-octadecadienoic acid methyl ester (10.15%), 11-eicosenoic acid (9.67%), hexadecanoic acid (8.63%), 13-docosenoic acid (5.20%). The oil was extracted by two different methods (soxhlet and maceration) and each sample was screened separately for antimicrobial activity against a panel of pathogens.

Keywords:

Negella sativa, Fixed oil, GC-MS, Antimicrobial activity.

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