Recent advancement in psoriasis and nanotechnological approaches for psoriasis management

Masarrat Majid Khan*, Maria Saifee, Farheen Nusrat Mazher Khan

Y B Chavan College of Pharmacy, Chhatrapati Sambhajinagar, Maharashtra, India

Refer this article

Masarrat Majid Khan, Maria Saifee, Farheen Nusrat Mazher Khan, 2026. Recent advancement in psoriasis and nanotechnological approaches for psoriasis management. Journal of medical pharmaceutical and allied sciences, V 15, I 3, Pages 24 – 31. Doi: https://doi.org/10.55522/jmpas.V15I3.7021

ABSTRACT

Significant progress has been made in understanding the pathophysiology of inflammatory skin disorders such as psoriasis and dermatitis. Advances in knowledge of age-related factors, gender differences, and genetic predisposition have helped clarify the complex mechanisms underlying these conditions, enabling the development of innovative therapeutic strategies. This review outlines the molecular and immunological pathways involved in psoriasis, highlighting key mediators responsible for disease initiation and progression. It also discusses both conventional and emerging treatment options, with emphasis on therapies developed over the past decade. Particular focus is placed on advanced drug delivery systems, including microneedle-based technologies and nanotechnology-driven approaches, which enable targeted delivery, improved bioavailability, and enhanced therapeutic efficacy. These emerging strategies show strong potential to improve clinical outcomes, enhance patient adherence, and provide more effective management of psoriasis and other chronic inflammatory skin disorders.

Keywords:

Psoriasis, Inflammatory skin diseases, Molecular mechanisms, Targeted drug delivery and nanotechnology

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