Effects of Methanolic Extracts of Quisqualis Indica (aerial parts) on passive smoking induced Hyperlipidemia in Rats

Jyoti Sahu*, Pushpendra Kumar Patel, Balkrishna Dubey

Department of Pharmacology, T.I.T. College of Pharmacy, Bhopal, Madhya Pradesh, India

Refer this article

Jyoti Sahu, Pushpendra Kumar Patel, Balkrishna Dubey, 2012. Effects of methanolic extracts of quisqualis indica (aerial parts) on passive smoking induced hyperlipidemia in rats. Journal of medical pharmaceutical and allied sciences, V 1 - I 1, Pages - 25 – 28. Doi: https://doi.org/10.55522/jmpas.V1I1.0005.

ABSTRACT

Background- Treatment of hyperlipidemia is important for prevention coronary heart disease. It has been proven that passive smoking causes approximately 50 000 deaths annually in the United States and it can be reduced by increased dietary intake of antioxidants which is a vast source of plant extracts. Objective- Study of  hypolipidemic activity of methanolic extracts of aerial parts of Quisqualis indica (QI) including flowers on passive smoking (PS) induced hyperlipidemia in rats had been evaluated. Method- Hyperlipidemia was induced by passive smoking in a closed chamber having 1 burning cigarette inside it. The hypolipidemic activity was analyzed by reading the blood serum level in UV at 505 nm after treated with reagent present in auto span diagnostic kit. Results- Methanolic extracts of QI significantly reduce the harmful lipid layer in blood serum at varying concentration and dose dependent manner which shows that the plant carries the hypolipidemic properties. It reduces the LDL, VLDL, cholesterol, triglyceride and raise HDL level in blood serum.

Keywords:

Hypolipidemic, Hypocholesterolemic, Passive smoking (PS), Hyperlipidemia, Quisqualis indica.

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