MICRO EMULSION BASED GEL: RECENT EXPANSIONS FOR TOPICAL DRUG DELIVERY SYSTEM

Patel R. R*., Patel Z. K, Patel K. R., Patel M. R.

ABSTRACT

Micro emulsion based Gel formulation provides better application property and stability & makes it dual control release system in comparison to cream and ointment. Topical Micro emulsion based gel drug administration is a localized drug delivery system anywhere in the body through ophthalmic, rectal, vaginal and skin as topical routes. Many advantages of gels a major limitation is in the delivery of hydrophobic drugs. So to overcome this limitation Micro emulsion based approach is being used so that even a hydrophobic therapeutic moiety can enjoy the unique properties of gels. When gels and Micro emulsions are used in combined form the dosage form are referred as Micro emulsion based gel. It is prepared by mixing an oil-in-water type or waterin- oil type emulsion with a gelling agent. The use of Micro emulsion based gels can be extended in analgesics and antifungal drugs.

Keywords: Antifungal activity, Gelling agent, Hydrophobic drugs, Micro emulsion gel, Topical drug delivery