Evaluation of antifungal activity of Lageneria Siceraria seeds for ringworm infection

ABSTRACT

Lageneria siceraria commonly known as Bottle gourd Syn. Doodhi , Synonyms Lauki (Hindi) Kadoo ( Marathi) which is official in Ayurvedic Pharmacopoeia Preliminary phytochemical screening of the crude extracts revealed the presence of carbohydrates , Proteins etc and secondary metabolites like saponins , glycosides , alkaloids etc .Thus, the study is carried out in order to determine the antifungal (ringworm) activity of the seeds of the plant. The seeds of the plant are subjected to extraction with water and ethanol. The antifungal activity was carried out using agar well diffusion method. All the plant extracts were compared with standard Isoconazole (1% w/w) as positive control and distilled water, ethanol used as negative control. Accordingly ethanolic extract of the roots was found to more effective against Trichophyton rubrum as compared to aqueous extract.

Keywords: Lageneria siceraria, alkaloids, extraction