ANTIPYRETIC ACTIVITY OF ETHANOLIC EXTRACT OF PROSOPIS CINERARIA PODS

Abhishek Pandey1, 2*, Atul Kaushik2, Suman Jain3, Bhagat Singh Jaiswal3

1. Department of Pharmaceutical Sciences, IFTM University, Moradabad, (U.P.) India. 

ABSTRACT

Prosodies cineraria used in folk medicine to treat various ailments such as anemia, arthritis, asthma, toothache, ulcers and vertigo. Prosopis cineraria bark is used as remedy against the rheumatism, fever and inflammation. Pods is used for earache, toothache, pain relief from fractured bones. The aim of present study is to evaluate the antipyretic effect of Prosopis cineraria pods. Phytochemical screening of Prosopis cineraria pods were carried out to determine the presence of various phytoconstitutents. Antipyretic effect was evaluated by Brewer’s yeast induced pyrexia method. Phytochemical screening revealed presense of various secondary metabolites. Ethanolic extract of Prosopis cineraria pods (PCEE) show significant Antipyretic activity at dose 400 mg/kg. The results indicate that ethanolic extract of Prosopis cineraria pods can be a good candidate for reducing fever and validates its use as useful folk medicine due to presence of various secondary metabolites.

Keywords: Pods, Pyrexia, Prostaglandins, Brewers yeast, Arid zone