Abdel Karim. M.1*Sufian,A.2 Kamal M.S.2

DOI:

VOLUME-6, ISSUE-03

MS Analysis and Antimicrobial Activity of Fixed Oil From Saudi Peganum harmala L. (Zygophyllaceae)

Abdel Karim. M.1*

Sufian,A.2

Kamal M.S.2

1- Sudan University of Science and Technology, Faculty of Science, Dept. of Chemistry

2- Taiba University , Faculty of Science, Dept. of Chemistry.

ABSTRACT

In this study the lipid composition of Saudi material of Peganum harmala (L.) seeds was identified and quantified. The antimicrobial activity of the extracted fixed oil was assessed . The following major components were detected : 9,12– octadecadienoic acid (56.08%),9-octadecenoic acid (22.35%) , hexadecanoic acid methyl ester(9.24%), , methyl stearate(4.56%). The fixed oil was extracted by two different methods (soxhlet and maceration). Each sample was screened for antimicrobial activity using cup plate agar diffusion assay against eight standard human pathogens. The influence of .the method of extraction on the antimicrobial activity was investigated.

Keywords: Peganum harmala , Fixed oil ,GC-MS, Antimicrobial Activity.

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