AN OVERVIEW STUDY ON NASAL AND INTRANASAL DELIVERY SYSTEM OF DRUG

Barethiya Varsha*, Kukde Abhijeet, Rajbhar Kusum, Dixit Gouri

Priyadarshini J.L. College of Pharmacy, Nagpur, Maharashtra, India

ABSTRACT

Researchers and scientists make an incredible attempt to deliver the active medicaments in the various dosage forms for getting an effective therapeutic action. Several routes for drug administration are available presently with their promising effects and acceptance by the patients. Among this various drug delivery systems, nasal and intranasal route of drug delivery is found to be more promising as it is minimizing the shortcomings of oral and parenteral route. It is the only drug delivery systems which delivered the active medicament to the brain. It is found more valuable to treat the brain related disorders by administering the drug through the intranasal route. Hence, this delivery system is having a large surface area and found effective at low concentration of drug doses with the ease of drug administration, convenient and better patient compliance.

Keywords:

Nasal cavity, retention time, mucociliary clearance, CNS disorders, antihistamines