NON-ALCOHOLIC WERNICKE ENCEPHALOPATHY COMPLICATING WITH HYPEREMESIS GRAVIDUM

Bulla Sri Vidya*, Shaik Ameena, Nandyala Bhargavi Reddy, Ramavathu Vijaya Shree, Dr. K. Lakshmi Prasunna

Nirmala College of Pharmacy, Mangalgiri, Guntur, Andhra Pradesh, India

ABSTRACT

Wernicke Encephalopathy is a deadly illness mostly seen in alcoholics as a consequence of deficiency in thiamine intake, it primarily targets the nervous system. This article reports an unusual case of Non-Alcoholic Wernicke Encephalopathy in a 28 years old female patient, with 17 weeks of gestation, complaints of severe hyperemesis gravidum. Patient presented with SOB, Nystagmus, Opthalmoplegia and altered speech since 2 weeks. MRI Brain has shown hyperintense signals on T2W FLAIR in bilateral thalami, periaqueductal grey matter and mammillary bodies. The case was managed with 500mg Thiamine given twice daily and other supplementary treatment, patient had underwent an Intrauterine fetal demise followed by cardiac arrest

Keywords:

Hyperemesis Gravidum, Nystagmus, Opthalmoplegia, Milaria Crystallina.