SCREENING, IDENTIFICATION AND ISOLATION OF SOME FUNGAL SPECIES AGAINST OPPORTUNISTIC FUNGAL PATHOGEN CANDIDA ALBICANS

Aakriti Shukla*, Dr. Apoorva Pathak

Sri Satya Sai University of Technology & Medical Sciences Sehore, Madhya paradesh, IndiaCorrespondence

ABSTRACT

Candida albicans or Monilia albicans is an opportunistic fungus, it is basically present on the skin and mucous membranes such like vaginal area, mouth, or rectum part. Candida albicans can travel through the blood and affects intestines, throat, and heart valves of healthy as well as immunocompromised individual. When is there is any change in body temperature Candida albicans becomes an infectious agent and it starting grow out of control it also cause life threating infections to patients with weak immunity (AIDS), patients in ICU and undergoing Chemotherapy. Some of the Candida infections could be treated with home remedies, topical creams or with prescription medication such as clotrimazole, miconazole, nystatin, tioconazole, or oral administration of drugs such as fluconazole and amphotericin B. Although all this antifungal drug helps in getting cure the trouble, but the infection can recur. As per the ongoing research on all over the globe, it has been proven that Candida albicans become resistant over most the drug, so it is necessary to find an alternative drug to cure this life-threatening organism. In the present study we evaluated and screened the secondary metabolites of fungi for the control of Candida albicans by evaluating the potential of fungal bioactive compounds, its purification and characterization.

Keywords:

Candida, Metabolites, Infectious agents, bioactive compounds.