Bambuterol hydrochloride, In-situ nasal gel, Controlled drug release, Gelling temperature, Stability studies

Rima Ramesh Patil*, Prashant L. Pingale

SNJB’s Shriman Sureshdada Jain College of Pharmacy, Chandwad, Nashik, Maharashtra, India

ABSTRACT

Significant progress has been achieved in the creation of novel drug delivery systems based on herbal bioactive in recent years. Herbal formulations for novel drug delivery systems are more efficient and have more benefits than other alternatives. Papaya (Carica papaya Linn) is very popular for its nutritious as well as therapeutic benefits all over the world. Carica papaya is a tropical and subtropical fruit that is used as a vegetable and in herbal medicine to treat a variety of ailments. The rising prevalence of diabetes, along with the harsh side effects of some synthetic drugs, has prompted an increase in the search for natural alternatives. Liposomes, phytosomes, ethosomes microspheres, nano-capsules, transferosomes, polymeric nanoparticles, nano-emulsions, and nano-emulsions have all been developed using bioactive and plant extracts. The primary motivation for the advancement of alternative drug delivery is to improve drug delivery quality and safety while also providing greater patient comfort.

Keywords:

Nano-carrier, Bioactive, Anti-diabetic, Herbal remedies