Evaluation of nephroprotective and antioxidant potential of Cucumis pubescens in rats

Harish Kumar*, Sunil Sharma, Neeru Vasudeva

Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India

ABSTRACT

To find the effective way of treatment of diabetic nephropathy with herbal medicine with modern allopathic medicines. In the present research study we use streptozotocin model (55mg/kg) for inducing the diabetes and development and progression of Diabetic may leads to various diabetic complication; Nephropathy is one of the imperative complication leads to renal physiological alteration. Various nephropathy evaluation parameters were assessed in this research study by various methods. Cucumis pubescencs an herb used for the treatment of the nephropathy along with the Antidiabetic drugs. The result obtained in the current research study showed that combination of herbal and modern allopathic medicine in experimentally induced diabetic nephropathy in rats were significantly aid in nephropathic complications. At present therapeutic scenario there are a lot of allopathic medicines in the market for the treatment of diabetes mellitus, but due to severe complication with the drugs therapy move towards the ayurvedic/Herbal treatment. At present some advance research is needed to explore the active phytoconstituents for the treatment of various ailments.

Keywords:

Diabetic, Cucumispubescens, herbal medicine, glucose