Comparative study of anthelmintic activity of leaves and bark of feronia limonia linn on indian earthworm

Hemant P Suryawanshi, Rajesh A Ahirrao, HS Hasni

Poojya Sane Guruji Vidya Prasarak Mandal’s, College of Pharmacy, Shahada, Maharastra, India

ABSTRACT

The Rutaceae family includes Feronia Limonia. Traditional uses include astringent, constipating, liver and lung tonic, diuretic, carminative, and cardiotonic effects in the plant's leaves, fruits, roots, and bark. Feronia Limonia has been shown to include alkaloids, phenolic compounds, triterpenoids, tannins, steroids, and other phytoconstituents. Only a few pharmacological activities have been scientifically documented, such as antimicrobial, antiviral, anticancer, and antifungal. Due to its vast traditional usage documented in several traditional systems of medicine and the presence of important phytoconstituents, Feronia Limonia is a significant plant that should be studied scientifically to prove a variety of traditional applications. The current study looks at Feronia Limonia's description, traditional medicinal uses, phytoconstituents, and anthelmintic activity of aqueous and alcoholic leaf and bark extracts. On adult Indian earthworms (Pheretima Posthuma), four concentrations (25, 50, 75, and 100 mg/ml) of aqueous and alcoholic extract of leaves and bark of Feronia Limonia were tested for anthelmintic activity, which included determining the time of paralysis and death of the worms using Piperazine citrate as a reference standard. The results showed that a concentration of 100 mg/ml Feronia Limonia leaves had greater anthelmintic activity than other concentrations of aqueous and alcoholic extracts of bark and leaves

Keywords:

Feronia Limonia, Pheretima Posthuma, Phyto constituents, Anthelmintic