Nano diamonds a newer carrier for anti-cancer drug delivery system

Archana Dhyani, Partha Sarthi Bairy, Nardev Singh, Ashish Dhyani

Graphic Era Hill University, Dehradun, Uttarakhand, India

ABSTRACT

Nano diamonds had recently gained the importance in the field of biotechnology and biomedical science. Nan diamonds are biocompatible and can be complexes with chemotherapeutics. This opens the door of the Nano diamonds in treatment of cancer. The nano diamonds overcomes the problems associated with conventional therapy by providing the localized drug delivery, reduces the frequency of dosing and provide better patient compliance by overcoming the side effect of conventional chemotherapeutic treatment. In this manuscript the authors focused on unique properties of nano diamonds. The different methods like Chemical Vapor Deposition, Detonation synthesis, High-pressure, high-temperature (HPHT) synthesis, Laser synthesis and Plasma Etching methods were discussed for the formulation of Nanodiamonds. The manuscript also gives an insight into the importance of nanodiamonds in ontological studies along with in-vitro and in-vivo biocompatibility study of nano diamonds.

Keywords:

Nano diamonds, Bio-compatibility, Cytotoxicity, Chemotherapeutics, Anticancer, Oncology