Physiochemical characterization of silver nanoparticles using rhizome extract of Alpinia galanga and its antimicrobial activity

Pankaj Nainwal, Shatakshi Lall, Akbar Nawaz

Graphic Era Hill University, Clement Town, Dehradun, Uttarakhand, India

ABSTRACT

Nanoparticles feature one-of-a-kind, size-dependent characteristics, making them useful in a variety of fields. Nanoparticles are particularly fascinating for medicine and pharmacology because of their capacity to regulate their characteristics. The design of particular nanostructures that can be utilized as innovative diagnostic and therapeutic modalities is connected with the usage of nanoparticles in medicine. High biocompatibility, durability, and the potential of large-scale manufacturing without organic solvents are all benefits of noble metal-based nanoparticles, which are significant for medical applications. PXRD, UV-Vis, FESEM, and EDX, as well as FTIR and DLS, were used to describe with silver nanoparticles attached to Alpinia galanga rhizome extract. The extract was evaluated against some pathogens like E. coli, Pseudomonas’s., Staphylococcus’s. and Candida species, the enormously stable Alpinia galanga silver nanoparticles extract were shown to be promising as antibacterial and antifungal agents. The antibacterial and antifungal characteristics of AgNPs produced from Alpinia galanga rhizome extract function as a significant therapeutic medication for microbial infections illness and other health-related diseases.

Keywords:

Silver, Nanoparticle, Alpinia, Physiochemical, Antimicrobial